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Discover Supplement-Drug Interactions
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Last Updated: 3 months ago
supplement:
Glucosamine
drug:
Uridine
Research Papers that Mention the Interaction
“A 50% decrease in growth also persisted when uridine and cytidine, cytidine alone, or UDP, were added together with D-glucosamine.”
D-glucosamine-induced changes in nucleotide metabolism and growth of colon-carcinoma cells in culture.“ D-Glucosamine inhibited the incorporation of labeled uridine and amino acids into acid-precipitable material.”
The inhibition of thymidine kinase in glial tumor cells by an amino sugar, D-glucosamine.“For [3H]glucosamine , pretreatment with uridine resulted in a reduction of the glycosylation in both fractions.”
The effect of increasing nucleotide-sugar concentrations on the incorporation of sugars into glycoconjugates in rat hepatocytes.“Furthermore the complete resumption of the capacity to incorporate either 3H-thymidine or 3H-mannose which was observed after the removal of the aminosugar, was impeded when the cells were treated contemporaneously with D-glucosamine and uridine.”
“ Glucosamine also reduced the uridine nucleotide pool sizes, and accumulated uridine diphosphate (UDP)-N-acetylglucosamine.”
“ Uridine reverses partially the glucosamine inhibition of protein biosynthesis.”
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