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Discover Supplement-Drug Interactions

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Possible Interaction: Glucosamine and Tretinoin

supplement:

Glucosamine

supplement:

Tretinoin

Research Papers that Mention the Interaction

RA increased the incorporation of glucosamine and galactose but not mannose into high molecular weight (HMW) glycoconjugates of about 220 and 500–600 kDa.
Glycoconjugate Journal  •  1996  |  View Paper
Exposure of the fibroblast cultures to retinoic acid (10(-6) mol/l) and retinyl propionate (2 x 10(-6) mol/l) resulted in a decrease in the incorporation of [3H]glucosamine into hyaluronate by up to 41% in monolayer cultures, and 25% in collagen lattice cultures.
The retinoids stimulated the incorporation of [3H]glucosamine into heparan sulphate by up to 72%, and chondroitin sulphates by up to 30%, whereas 35SO4 incorporation remained essentially unaltered.
The British journal of dermatology  •  1995  |  View Paper
Possible mechanisms for the inhibition of the aggrecanase response by glucosamine in chondrocytes treated with IL-1 or RA are discussed.
The Biochemical journal  •  1998  |  View Paper
The results … that retinoic acid enhanced [3H]glucosamine incorporation into a Mr 160,000 glycoprotein in the S91-C-2 cells but not in any of the resistant mutant clones, while the pattern of [35S]methionine-labeled proteins was not modified in either the sensitive or the resistant clones.
Cancer research  •  1984  |  View Paper
5. (5) Intraperitoneal injection of deficient rats with retinoic acid decreased the incorporation of [ 14 C]glucosamine into the TCA-insoluble fraction of the retina to a level which was not significantly different from that observed in the control.
Experimental eye research  •  1977  |  View Paper