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Discover Supplement-Drug Interactions

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Last Updated: 7 months ago

Possible Interaction: Glucosamine and Interferons

supplement:

Glucosamine

Research Papers that Mention the Interaction

At 80 mM d -glucosamine or at 8 mM 2-deoxy- d -glucose, interferon production was inhibited by approximately 95%; however, at 20 and 2 mM, respectively, these inhibitors allowed interferon production at about 50% of levels produced by leukocytes not treated with the inhibitors.
Virology  •  1979  |  View Paper
Interferon production was inhibited in the Namalwa line of human lymphoblastoid cells by treatment with 2-deoxy-D-glucose or D-glucosamine.
The Journal of general virology  •  1979  |  View Paper
Interferon synthesized in the presence of partially inhibitory concentrations of 2-deoxy-D-glucose or D-glucosamine were found to differ from interferons made in control cultures in some physical properties.
The Journal of biological chemistry  •  1977  |  View Paper
Residual active interferon made in the presence of d -glucosamine was less efficiently neutralized by anti-interferon antibody than control interferon.
Virology  •  1975  |  View Paper
Galactose (±uridine), glucosamine (±uridine), and N‐acetylmannosamine (ManNAc) (±cytidine) feeding resulted in 12%, 28%, and 32% increase in IFN‐γ sialylation as compared to the untreated control cultures.
Biotechnology and bioengineering  •  2010  |  View Paper
The present data show that GlcN , but not GlcNAc, inhibits CD4+ T‐cell proliferation, the generation of alloreactive cytotoxic T lymphocytes (CTLs) and the secretion of interferon‐γ (IFN‐γ) and interleukin‐5 (IL‐5) in primary MLC.
Scandinavian journal of immunology  •  2003  |  View Paper
Glycosylation inhibitors like glucosamine were uneffective on interferon induction 'in vivo'.
Chemotherapy  •  1983  |  View Paper