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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Glucosamine
drug:
Ibuprofen
Research Papers that Mention the Interaction
“Combinations containing racemic ibuprofen and glucosamine in greater than 1:1 ratio (glucosamine/ibuprofen) were synergistic in the test (e.g., ED50 = 11.0 ± 2.1 for the 9:1 ratio; p < 0.01, analysis of variance).”
Antinociceptive Synergy, Additivity, and Subadditivity with Combinations of Oral Glucosamine Plus Nonopioid Analgesics in Mice“The results also showed that although GL can enhance the solubility of Ibu , it also reduces pH around the Ibu particles which led to poor dissolution performance when the concentration of GL is high.”
The dissolution and solid-state behaviours of coground ibuprofen–glucosamine HCl
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