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Discover Supplement-Drug Interactions

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Last Updated: a year ago

Possible Interaction: Glucosamine and Ibuprofen



Research Papers that Mention the Interaction

Combinations containing racemic ibuprofen and glucosamine in greater than 1:1 ratio (glucosamine/ibuprofen) were synergistic in the test (e.g., ED50 = 11.0 ± 2.1 for the 9:1 ratio; p < 0.01, analysis of variance).
Journal of Pharmacology and Experimental Therapeutics  •  2003  |  View Paper
The results also showed that although GL can enhance the solubility of Ibu , it also reduces pH around the Ibu particles which led to poor dissolution performance when the concentration of GL is high.
Drug development and industrial pharmacy  •  2015  |  View Paper