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Discover Supplement-Drug Interactions

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Possible Interaction: Glucosamine and Hyaluronan

supplement:

Glucosamine

supplement:

Hyaluronan

Research Papers that Mention the Interaction

In parallel with the opposing actions of these aminosugars on glucose transport, GlcN inhibits hyaluronan and SGAG synthesis while GlcNAc stimulates hyaluronan synthesis.
Osteoarthritis and cartilage  •  2009  |  View Paper
On the other hand, 2 mm glucosamine in the culture medium increased UDP-HexNAc content, stimulated hyaluronan secretion, and negated the effect of mannose, supporting the notion that the inhibition by mannose on hyaluronan synthesis was because of down-regulated UDP-HexNAc content.
The Journal of biological chemistry  •  2008  |  View Paper