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Last Updated: 7 months ago

Possible Interaction: Glucosamine and Glucose

supplement:

Glucosamine

supplement:

Glucose

Research Papers that Mention the Interaction

Uptake of 2-DG increased upon GlcN treatment under 5 mM glucose compared to control, whereas insulin-stimulated 2-DG uptake decreased under 5 mM and increased under 25 mM glucose in differentiated 3T3-L1 cells.
Metabolism: clinical and experimental  •  2015  |  View Paper
The effects of sorbitol, fructose and elevated concentrations of glucose were partly inhibited by ethanol, glycerol and glucosamine.
The Biochemical journal  •  1997  |  View Paper
Furthermore, … stimulated GC by ∼ 2.5-fold during saline infusion (from 3.0 ± 0.6 to 7.7 ± 1.4 mg.…−1 · min−1, P < 0.001, euglycemia vs. hyperglycemia), this increase was blunted in the presence of GlcN (4.6 ± 0.6 mg.…−1 · min−1, P = NS).
Diabetes  •  1996  |  View Paper
Administration of glucosamine 10 min before an infusion of glucose (10 mg · min−1 · 15 min) reduced the insulin response.
Glucosamine (5 mmol/l) reduced glucokinase activity in islet homogenate and diminished the insulin response to glucose (200 mg/dl) by isolated islets, whereas the response to arginine (20 mmol/l at 100 mg/dl glucose) was unaffected.
Diabetes  •  1994  |  View Paper
GlcN non-competitively inhibits basal glucose transport, which in part depends on GlcN-mediated depletion of ATP stores.
Osteoarthritis and cartilage  •  2009  |  View Paper
The production of CO2 from glucosamine by intact PMNs was inhibited by glucose and dependent upon activation of the hexosemonophosphate shunt (HMPS).
Inflammation  •  2004  |  View Paper
RESULTS In each group of patients, 25 mM D- lucose si gnificantly reduced the incorporation of [3H ]glucosamine (P <0.01), but not [35S]sulphate.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association  •  2002  |  View Paper
Interestingly, excess glucose rescued this glucosamine-mediated regulation, suggesting a functional competition between glucose and glucosamine.
The Journal of Biological Chemistry  •  2015  |  View Paper
Glucosamine (GlcN) increased glucose production and gluconeogenic enzyme (G6Pase and PEPCK) expression.
Stem cells and development  •  2014  |  View Paper
Conversely, culture with glucosamine , which increases the hexosamine pathway flux, impaired [Ca2+]i response to 8.3 mM glucose , mimicking HG.
Aging  •  2014  |  View Paper
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