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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Glucosamine
supplement:
Butyric Acid
Research Papers that Mention the Interaction
“Very low concentrations of 4-phenyl butyric acid (PBA, a chemical chaperone) inhibited only the overactivation of ER stress and UPR elicited by GlcN , leaving unaltered the part physiologically activated during differentiation, and reversed the inhibitory effect of GlcN on differentiation.”
Pathologic endoplasmic reticulum stress induced by glucotoxic insults inhibits adipocyte differentiation and induces an inflammatory phenotype.“Treatment of McA‐RH7777 cells with 4‐phenyl butyric acid , a chemical ER stress inhibitor, prevented glucosamine‐ and tunicamycin‐induced increases in GRP78 and phosphorylated eIF2α, rescued newly synthesized [35S]‐labeled apoB100, and substantially blocked the colocalization of apoB with GFP‐LC3.”
Hepatic autophagy mediates endoplasmic reticulum stress–induced degradation of misfolded apolipoprotein B
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