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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Glucosamine
drug:
4-Phenylbutyric Acid
Research Papers that Mention the Interaction
“In addition, GlcN stimulated proinflammatory cytokine release and PBA prevented these effects.”
“Very low concentrations of 4-phenyl butyric acid PBA , a chemical chaperone) inhibited only the overactivation of ER stress and UPR elicited by GlcN , leaving unaltered the part physiologically activated during differentiation, and reversed the inhibitory effect of GlcN on differentiation.”
Pathologic endoplasmic reticulum stress induced by glucotoxic insults inhibits adipocyte differentiation and induces an inflammatory phenotype.
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