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Possible Interaction: Glucagon and Secretin



Research Papers that Mention the Interaction

Gastrointestinal hormones secretin , CCK-PZ, gastrin, and serotonin) modulate the glucose- and amino acids–induced secretions of insulin and glucagon , respectively.
American journal of therapeutics  •  2013  |  View Paper
In the small bowel, CCK, gastrin, motilin, VIP, and glucagon stimulate contractions, while secretin inhibits contractions.
World Journal of Surgery  •  2005  |  View Paper
Secretin had a faint effect upon the adenylyl cyclase activity and glucagon was completely inefficient at this level.
Bioscience reports  •  1993  |  View Paper
Secretin was 100-fold less effective as a competitor and glucagon competed poorly even at concentrations 10 000 times greater than that of the tracer molecule.
Canadian journal of physiology and pharmacology  •  1983  |  View Paper
Secretin , which, in the dog, has been reported to inhibit normal glucagon secretion, provoked a twofold increase in 3,500 dalton plasma glucagon concentration.
The American journal of medicine  •  1981  |  View Paper
Caerulein, however, failed to increase inhibition when glucagon and secretin were infused simultaneously.
The highest degree of inhibition was obtained by the combination of glucagon and secretin.
Acta hepato-gastroenterologica  •  1978  |  View Paper
W. P. Dyck and colleagues5 in 1970 found that, while an intravenous injection of just under 1 mg ofglucagon did not affect the resting output of pancreatic juice in man, it did inhibit the flow of juice stimulated by an infusion of pancreozymin and secretin.
British medical journal  •  1973  |  View Paper
However, the addition of glucagon to secretin showed additive effects on glycogenolysis.
Gastroenterologia Japonica  •  2007  |  View Paper
The inhibitory effect of glucagon on pancreatic exocrine secretion induced by endogenously released secretin was studied in 4 dogs with chronic pancreatic fistulas and open gastric fistulas.
World Journal of Surgery  •  2005  |  View Paper
Glucagon is structurally related to secretin but inhibits the effects of secretin and cholecystokinin (CCK) on pancreatic secretion in vivo.
Pancreas  •  1988  |  View Paper
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