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Last Updated: 2 years ago

Possible Interaction: Glucagon and Oxytocin

supplement:

Oxytocin

Research Papers that Mention the Interaction

Evidence in animals and man suggests that oxytocin can directly stimulate the secretion of glucagon from pancreatic islets.
Diabete & metabolisme  •  1990  |  View Paper
During insulin-induced hypoglycaemia, oxytocin potentiated the increases in plasma glucagon and adrenaline, while an inhibitory effect on plasma cortisol levels was still present.
In conclusion, in insulin-dependent (type 1) diabetic patients, oxytocin delivery enhances plasma glucagon and adrenaline levels in basal conditions and during insulin-induced hypoglycaemia.
In insulin-dependent (type 1) diabetic subjects (n = 7) with blunted counter-regulatory hormone response to hypoglycaemia, the same dose of oxytocin (0.2 mU/min over 60 min) increased basal plasma glucose and glucagon concentrations and lowered basal plasma cortisol concentration.
Hormone research  •  1989  |  View Paper
In the present study we show that oxytocin is also able to increase arginine-induced glucagon and insulin secretion in healthy human beings.
Diabete & metabolisme  •  1988  |  View Paper
Pharmacological doses of oxytocin administered in basal conditions evoked a rapid surge in plasma glucose and glucagon levels followed by a later increase in plasma insulin and adrenaline levels.
Hormone research  •  1988  |  View Paper
The ICAs of insulin and glucagon after oxytocin was injected were higher than those of the control.
Animal science journal = Nihon chikusan Gakkaiho  •  2014  |  View Paper
SummaryRecent reports indicate that oxytocin exerts direct effects on the release of insulin and glucagon from the endocrine pancreas of the rat.
Cell and Tissue Research  •  2004  |  View Paper
1 and 2, glucagon increased (P < .01) 1 h after oxytocin in saline and ergotamine cows.
Journal of animal science  •  2000  |  View Paper
Both AVP (10(-9)-10(-6) M) and OT (10(-8)-10(-5) M) increased glucagon release from In-R1-G9 cells in a concentration-dependent manner and AVP was approximately 30-fold more potent than OT in this aspect.
Life sciences  •  1998  |  View Paper
Intracerebroventricular injections of 200 ng oxytocin caused a significant rise not only of insulin but also of glucagon and glucose levels.
Subcutaneous injections of oxytocin increased insulin, glucagon and glucose levels significantly.
as seen in response to suckling in lactating rats-are accompanied by a rise of glucagon and glucose levels which is blocked by the oxytocin antagonist.
Neuroendocrinology  •  1996  |  View Paper
Abstract Previous studies have shown that infusion of oxytocin into normal dogs increased plasma levels of insulin and glucagon.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine  •  1994  |  View Paper
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