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Discover Supplement-Drug Interactions
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Last Updated: 4 years ago
drug:
Glucagon
supplement:
Oleic Acid
Research Papers that Mention the Interaction
“ OA at 30 microM increased glucagon release from isolated islets in the presence of low (2.8 mM) and elevated (8.3 mM) glucose concentrations.”
Oleic acid glucose-independently stimulates glucagon secretion by increasing cytoplasmic Ca2+ via endoplasmic reticulum Ca2+ release and Ca2+ influx in the rat islet alpha-cells.“It is concluded that the calorigenic actions produced by infusing oleic acid and glucagon are additive and mediated by independent mechanisms.”
“When glucagon infusion (1 .O pg/kg per min) was superimposed on that of oleic acid , plasma TGL decreased sharply and a liver TGL deposit developed.”
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