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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“Incubation experiments using the glucagon‐producing mouse pancreatic α‐cell line αTC1 clone 9 (αTC1.9) as well as isolated pancreatic islets of rats and mice revealed that melatonin increases glucagon secretion.”
Evidence of the receptor‐mediated influence of melatonin on pancreatic glucagon secretion via the Gαq protein‐coupled and PI3K signaling pathways“In conclusion, these findings revealed evidence that melatonin influences pancreatic glucagon expression and secretion as well as the peripheral glucagon action.”
“The results demonstrate that melatonin incubation significantly enhanced the expression as well as the secretion of glucagon.”
“Conversely, in SAMP8 mice, melatonin treatment decreased the expression of glucagon , GLUT2, somatostatin and insulin.”
Beneficial effect of melatonin treatment on age-related insulin resistance and on the development of type 2 diabetes
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