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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Glucagon
supplement:
Magnesium Cation
Research Papers that Mention the Interaction
“An increase of magnesium ions from 1.0 mMol/l to 2.5-7.5 mMol/l strikingly inhibits insulin and glucagon release by approximately 50%, which is compensated for insulin by increasing the Ca2+-content of the medium.”
The effect of potassium, calcium and magnesium concentration on insulin and glucagon secretion of the perfused dog pancreas.“Reduction in concentration of Mg++ in the assay medium or incubation of liver membranes for 5 min at 30° prior to addition of glucagon results in loss of response of adenyl cyclase to glucagon and in reduction in the effects of GTP on basal activity.”
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