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Possible Interaction: Glucagon and Glycine

supplement:

Glycine

Research Papers that Mention the Interaction

Supraphysiological plasma levels of glycine had a small but insignificant stimulatory effect on glucagon secretion.
The Journal of clinical endocrinology and metabolism  •  1975  |  View Paper
In normal subjects, glucagon elicited a prompt reduction in plasma amino acid levels that was greatest for alanine and glycine.
The New England journal of medicine  •  1970  |  View Paper
In these studies carried out on four subjects it has been shown that the plasma concentration of threonine, proline, glycine , alanine, lysine, arginine, citrulline, serine, cystine and histidine were very significantly lowered by catabolic doses of glucagon ( 3 4 -1 mg.
Metabolism: clinical and experimental  •  1969  |  View Paper
The rate of incorporation of C 14 from glycine into liver glycogen was increased by a previous injection of glucagon , and decreased by a previous injection of epinephrine.
Archives of biochemistry and biophysics  •  1956  |  View Paper
With SEC, the decline in monomeric glucagon over time was much lower when aged in glycine (pH 10) than when aged in Tris (pH 8.5) or in citrate (pH 3).
Journal of diabetes science and technology  •  2010  |  View Paper
Intraperitoneal injection of glucagon (33 or 100 micrograms/100 g body wt.) 25 min before killing of rats also resulted in a 3-fold or 10-fold (depending on dosage) increase in the rate of catabolism of glycine.
The Biochemical journal  •  1992  |  View Paper
Alanine, glycine , and serine induced a greater enhancement of both glucagon and insulin secretion than other amino acids.
The American journal of physiology  •  1991  |  View Paper
Glucagon stimulates 14CO2 production from [1-14C] glycine by isolated rat hepatocytes.
The Journal of biological chemistry  •  1989  |  View Paper
Addition … glucagon had no effect on the disappearance rate of Gly-… from the medium, but reduced accumulation rates of glycine (3.39 +/- 0.30 versus 1.42 +/- 30, p less than 0.01) and alanine (4.42 +/- 0.66 versus 1.35 +/- 0.39, p less than 0.01).
The Journal of biological chemistry  •  1986  |  View Paper
Modifying the carboxyl groups of glucagon with glycinamide or removing the COON-terminal residues with cyanogen bromide reduces Lmax to less than 25% of the level of glucagon.
Bioscience reports  •  1982  |  View Paper
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