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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Glucagon
supplement:
Glutathione
Research Papers that Mention the Interaction
“ Glucagon and a phorbol ester independently increased GSH efflux while both compounds decreased the effect of vasopressin.”
Characterization of vasopressin-mediated GSH efflux from Hep G2 cells: significance of protein kinase C.“It is known that glucagon leads to a decrease in hepatic glutathione (GSH) synthesis that in turn is associated with decreased postprandial insulin sensitivity.”
Acute Glucagon Induces Postprandial Peripheral Insulin Resistance“ Glucagon elicited the antioxidant response by increasing glutathione and decreasing protein carbonyl levels in hemolymph, decreasing both protein carbonyl and protein nitrotyrosine levels in CNS.”
“Treatment of cells from control rats with 50 nmol/L glucagon or 1 mmol/L db-cAMP decreased glutathione concentration by 25-43%.”
“Cellular cysteine level was unchanged despite the significant fall in GSH after glucagon or phenylephrine treatment.”
“Cholera toxin, dibutyryl cAMP (DBcAMP), and glucagon inhibited GSH synthesis in cultured hepatocytes by 25-43%.”
“We diverted the investigation from its original purpose to further study this novel action of glutathione and we report here that catecholamines and glucagon inotropic effects, and resulting metabolic coronary dilatation are enhanced by glutathione.”
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