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Last Updated: 2 months ago

Possible Interaction: Glucagon and Calcium Supplement

Research Papers that Mention the Interaction

Calcium appears to inhibit octreotide suppression of glucagon and insulin secretion in patients with glucagonoma and insulinoma, respectively.
Digestion  •  1996  |  View Paper
Finally, calcium mediates cellular responses to glucagon stimulation (3,4) and thus affects the hepatic glucose output.
Acta medica Scandinavica. Supplementum  •  1984  |  View Paper
Intravenous application of 1 mg glucagon causes a significant decrease of the magnesium, calcium , and phosphate concentrations in the serum.
Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete  •  1978  |  View Paper
Glucagon specifically inhibits the Ca2+ pump in liver plasma membranes independently of adenylate cyclase activation1.
Nature  •  1987  |  View Paper
Glucagon increased cytosolic calcium concentration through the PKA-mediated phosphorylation of inositol-1,4,5-trisphosphate receptors (InsP3Rs), which associate with CRTC2.
Nature  •  2012  |  View Paper
Glucagon treatment of the cell line caused a dose-dependent increase in cAMP concentration, activation of cAMP-dependent protein kinase (PKA), and transient release of intracellular calcium.
In addition, chelation of intracellular calcium reduced glucagon-mediated ERK1/2 activation.
Proceedings of the National Academy of Sciences of the United States of America  •  2001  |  View Paper
BACKGROUND Secretion of insulin and glucagon is triggered by elevated intracellular calcium levels.
PloS one  •  2011  |  View Paper
Chelation of intracellular calcium (intracellular [Ca(2+)]) reduced glucagon-mediated ERK1/2 activation.
The Journal of biological chemistry  •  2004  |  View Paper
Glucagon stimulated gluconeogenesis from lactate in duckling liver and the stimulation was 2.2-fold higher in CA than in TN fasted birds.
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology  •  2001  |  View Paper
In fura-2 AM loaded acinar cells both INS and GLU evoked small increases in intracellular free calcium concentration [Ca2+]i compared to a much larger elevation with ACh.
Peptides  •  1997  |  View Paper
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