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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Glipizide
supplement:
Serum Albumin, Human
Research Papers that Mention the Interaction
“ Glipizide preferentially interacts with sub-domain IIA of HSA and their complexion is thermodynamically favorable.”
Unravelling the interaction of glipizide with human serum albumin using various spectroscopic techniques and molecular dynamics studies“… glipizide was interacting … glycated HSA through two general groups of sites: a set of relatively strong interactions and a set of weaker interactions with average association equilibrium ….4 and 37 °C in the range of 2.4–6.0 × 105 and 1.7–3.7 × 104 M−1, respectively.”
“The islet content of sodium increased when 100 microM tolbutamide or 1 microM glipizide were added to an albumin-containing (1 mg ml-1) medium, but remained unaffected at 10-fold higher concentrations.”
Supramaximal decrease of sulphonylurea-induced accumulation of sodium in pancreatic islets.
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