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Discover Supplement-Drug Interactions

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Last Updated: 6 months ago

Possible Interaction: Gliclazide and St John's Wort

supplement:

St John's Wort

Research Papers that Mention the Interaction

Clinical trials indicate …’s wort Hypericum perforatum ), via cytochrome P450 (CYP) and/or P-glycoprotein induction, reduces the plasma concentrations (… the clearance) of alprazolam, amitriptyline, atorvastatin, chlorzoxazone, ciclosporin, debrisoquine, digoxin, erythromycin, fexofenadine, gliclazide , imatinib, indinavir, irinotecan, ivabradine, mephenytoin, methadone, midazolam, nifedipine, …, quazepam, simvastatin, tacrolimus, talinolol, verapamil, voriconazole and warfarin.
Drugs  •  2012  |  View Paper