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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“Furthermore, the production of malonaldehyde and carbonyl derivatives of proteins was also more effectively inhibited by co-treatment of genistein and stachyose , and thereby glutathione peroxidase and superoxide dismutase activities were elevated in HF-fed mice.”
“The potential mechanism was that stachyose enhanced absorption of genistein in HF-fed mice by oral supplementation of genistein together with stachyose.”
“These findings indicate that co-ingestion of stachyose and genistein may serve as a novel strategy for hepatic protection.”
“This study showed that co-administration of genistein and stachyose caused stronger inhibition on abnormal weight gain and liver fat accumulation by decreasing fatty acid synthetase expression and balancing disorderly lipid metabolism than that of genistein or stachyose alone in high-fructose (HF) diet-fed mice.”
Enhancing the hepatic protective effect of genistein by oral administration with stachyose in mice with chronic high fructose diet consumption.“Additionally, the simultaneous administration with stachyose and genistein in mice could decrease intestinal SULT, UGT, P-gp, and MRP1 expression, relative to the treatment with individual stachyose or genistein.”
“Furthermore, the feces level of genistein aglycone was also elevated by co-treatment of stachyose with genistein.”
Non-digestible stachyose promotes bioavailability of genistein through inhibiting intestinal degradation and first-pass metabolism of genistein in mice
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