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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Genistein
supplement:
Soy Isoflavones
Research Papers that Mention the Interaction
“After the evening intake … dose of an isoflavone-rich soy protein isolate drink, the early … blood levels of genistein and daidzein were higher in seven dialysis patients than in eight healthy subjects (genistein 1271+/-… versus 425+/-104, P<0.05; daidzein 1304+/-352 versus 292+/-78, P<0.05).”
Serum levels and metabolic clearance of the isoflavones genistein and daidzein in hemodialysis patients.“Oral administration of soy isoflavones gives plasma concentrations of genistein that have been associated with antimetastatic activity in vitro.”
“Previous research in our lab found that once daily oral treatment of ovariectomized female Long-Evans (LE) rats with the soy phytoestrogen, genistein resulted in subtle deficits in performance on cognitive tasks assessing working memory and response inhibition/timing ability.”
“In analyses conducted in cases and controls separately, levels of plasma genistein , daidzein and total isoflavones increased with increasing levels of self-reported intake of soy isoflavones.”
“Liver iodothyronine deiodinase types 1 and 2 (Dio1 and Dio2) mRNA levels were increased with SPI diet; the effect on Dio2, but not Dio1 mRNAs, also was observed with GEN.”
Soy protein diet alters expression of hepatic genes regulating fatty acid and thyroid hormone metabolism in the male rat.
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