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Discover Supplement-Drug Interactions

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Last Updated: 4 years ago

Possible Interaction: Genistein and Sorafenib

supplement:

Genistein

drug:

Sorafenib

Research Papers that Mention the Interaction

“In addition, genistein enhanced the antitumour effect of sorafenib in sorafenib-resistant HCC cells and HCC-bearing mice.”
Genistein suppresses aerobic glycolysis and induces hepatocellular carcinoma cell death
British Journal of Cancer  •  2017  |  View Paper
“Our results suggested that combination of SF and GST inhibited angiogenic and survival factors and increased apoptosis via receptor and mitochondria mediated pathways in both neuroblastoma SK-N-DZ and SH-SY5Y cell lines.”
Synergistic efficacy of sorafenib and genistein in growth inhibition by down regulating angiogenic and survival factors and increasing apoptosis through upregulation of p53 and p21 in malignant neuroblastoma cells having N-Myc amplification or non-amplification
Investigational New Drugs  •  2009  |  View Paper