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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“Furthermore, the author also demonstrated that leptin upregulates ERK pathway, which was inhibited by genistein [6, 7].”
Comment on “Effects of adipocyte-secreted factors on cell cycle progression in HT29 cells” published by Eur J Nutr“ Genistein (5 μM) significantly inhibited both the proliferation and migration of leptin (10 ng/ml)‐stimulated A10 cells.”
“ Genistein was capable of suppressing the atherogenic effects of leptin in vitro and in vivo, and may be a promising candidate drug in the clinical setting.”
“Here, we investigated whether genistein suppressed the atherogenic effect induced by leptin.”
Genistein suppresses leptin‐induced proliferation and migration of vascular smooth muscle cells and neointima formation“… genistein significantly altered maternal T3, (GD18; Con 1.65 ± 0.01, Gen … 29.60 ± 0.00, Gen 36.04 ± 1.29 nmol/L), Leptin (Placenta GD20; Con 0.08 ± 0.01, Gen 0.31 ± 0.02 ng/… ± 0.00, Gen 0.35 ± 0.05 ng/ml) in genistein group.”
“ Leptin secretion stimulated by glucose with insulin was significantly diminished by genistein (0.25--1mM).”
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