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Last Updated: 3 years ago

Possible Interaction: Genistein and Kaempferol

supplement:

Genistein

supplement:

Kaempferol

Research Papers that Mention the Interaction

Genistein is a potent inhibitor of tyrosine kinases and along with flavonoids such as kaempferol and apigenin is also an inhibitor of topoisomerases I and II, enzymes which are crucial to cellular proliferation.
European Urology  •  1999  |  View Paper
Interestingly, effects of the mixture of genistein and kaempferol were stronger than those revealed by any of these compounds used alone.
Scientific reports  •  2015  |  View Paper
On the other hand, while quercetin, daidzein and luteolin did not alter the activity of CDK1, kaempferol, apigenin and genistein inhibited this kinase by 50-70%.
Biochemical pharmacology  •  2001  |  View Paper
Luteolin concentration showed a significant negative correlation with genistein (r2 = −0.45*).
Journal of dietary supplements  •  2017  |  View Paper