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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Genistein
supplement:
Indole-3-Carbinol
Research Papers that Mention the Interaction
“ResultsHere we found for the first time that co-treatment with I3C and genistein , derived from cruciferous vegetables and soy, respectively, synergistically suppressed the viability of human colon cancer HT-29 cells at concentrations at which each agent alone was ineffective.”
“These results give rise to the possibility that co-treatment with I3C and genistein induces apoptosis through the simultaneous inhibition of Akt activity and progression of the autophagic process.”
A combination of indol-3-carbinol and genistein synergistically induces apoptosis in human colon cancer HT-29 cells by inhibiting Akt phosphorylation and progression of autophagy“A combination of I3C and genistein gave greater than expected induction of BRCA expression.”
“Because of the synergistic effect of I3C and genistein , the potential exists for prophylactic or therapeutic efficacy of lower concentrations of each phytochemical when used in combination.”
“We show a synergistic effect of I3C and genistein for induction of GADD expression, thus increasing apoptosis, and for decrease of expression driven by ER-alpha.”
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