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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Genistein
drug:
Collagenases
Research Papers that Mention the Interaction
“When RMC were retreated with genistein and herbimycin A, both inhibited collagenase mRNA induction by IL-1 beta.”
Interleukin-1 beta induces interstitial collagenase gene expression and protein secretion in renal mesangial cells.“Similarly, collagenase steady-state mRNA levels and the activity of a transfected human collagenase-promoter CAT construct were inhibited by genistein and enhanced by orthovanadate.”
“As with the rosette formation, genistein also inhibits the increased expression of the 92-kDa collagenase.”
Hypoxia-induced alterations in cytoskeleton coincide with collagenase expression in cultured neonatal rat cardiomyocytes.
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