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“ Genistein is a potent inhibitor of tyrosine kinases and along with flavonoids such as kaempferol and apigenin is also an inhibitor of topoisomerases I and II, enzymes which are crucial to cellular proliferation.”
Journal of biochemical and molecular toxicology • 2010 | View Paper
“ Genistein at 10–5 M was inhibitory, while apigenin significantly potentiated the response at 19–7 M. In contrast, DDT had no effect on the FSH-induced response, though 10–7 M octyl-phenol nearly doubled the response.”