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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Genistein
Research Papers that Mention the Interaction
“Interestingly, flavonoids with chemopreventative effects, such as quercetin, genistein , and epigallocatechin gallate activate ATM.”
Pharmacologic manipulation of the ataxia-telangiectasia mutated gene product as an intervention in age-related disease.“ Genistein stimulates p21(waf1/cip1) and cyclin B1 expression, phosphorylation/activation of ATM and Chk2 kinases, and Tyr15-phosphorylation/inactivation of Cdc2 (Cdk1) kinase, and these effects are attenuated by MEK/ERK inhibitors, while LY294002 also attenuates ERK and ATM phosphorylation.”
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