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Discover Supplement-Drug Interactions
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Last Updated: 4 years ago
supplement:
Genistein
drug:
Afimoxifene
Research Papers that Mention the Interaction
“ Genistein- and equol-induced cell proliferation and S-phase entry were blocked by the ERalpha antagonists 4-hydroxytamoxifen and ICI 182,780 and by the mitogen-activated protein kinase 1/2 inhibitor U0126.”
“The ERE-reporter activity induced by daidzein, genistein , and kaempferol was blocked by both ICI 182780 and 4-hydroxytamoxifen and partly blocked by puerarin.”
Phytoestrogens induce differential estrogen receptor β-mediated responses in transfected MG-63 cells“This protection was mimicked by an ER agonist, genistein (0.1 mg/kg), and prevented by an ER antagonist, 4-hydroxytamoxifen (2 mg/kg).”
17beta-estradiol affords protection against 4-vinylcyclohexene diepoxide-induced ovarian follicle loss in Fischer-344 rats.“This protection was mimicked by an ER agonist, genistein (0.1 mg/kg), and prevented by an ER antagonist, 4-hydroxytamoxifen (2 mg/kg).”
17β-Estradiol Affords Protection against 4-Vinylcyclohexene Diepoxide-Induced Ovarian Follicle Loss in Fischer-344 Rats.
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