supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
drug:
Gemfibrozil
supplement:
Genistein
Research Papers that Mention the Interaction
“Co‐perfusion with genistein also significantly decreased the biliary extraction ratio of hepatically generated GG from 0.95 + 0.01 to 0.83 + 0.05.”
“… genistein … GG from a mean of 0.82 to 0.65 and the first‐order rate constant for transport of GG into bile from 0.054 + … increased the first‐order rate constant for sinusoidal efflux of GG from 0.128 + 0.023 to 0.227 + 0.078 min−1.”
The effects of the phytoestrogenic isoflavone genistein on the hepatic disposition of preformed and hepatically generated gemfibrozil 1‐O‐acyl glucuronide in the isolated perfused rat liver
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback