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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Gemcitabine and Indole-3-Carbinol

Research Papers that Mention the Interaction

However, combining gemcitabine with I3C further increased hENT1 expression.
Recently, published data from our laboratory demonstrated enhanced efficacy of gemcitabine with the dietary agent, indole-3-carbinol (I3C).
This study demonstrates that up-regulation of hENT1 expression may be a novel mechanism involved in the additive effect of I3C and gemcitabine.
Anticancer research  •  2011  |  View Paper
This study demonstrated the ability of dietary agent, indole-3-carbinol (I3C), to lower the LD(50) of gemcitabine (Gemzar) in decreasing growth of both male (MiaPaca2) and female (SU86.86) pancreatic cancer cells.
Anticancer research  •  2010  |  View Paper