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Discover Supplement-Drug Interactions
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Last Updated: 4 years ago
supplement:
Garlic
supplement:
Oil Of Garlic
Research Papers that Mention the Interaction
“RESULTS Extracts of fresh garlic, different brands and lots of odourless garlic and representative samples of ga lic oil, f reeze dried garlic, and aged gar lic ex hibited an inhibitory effect on cytochrome P450 2C9*1, 2C19, 3A4, 3A5 and 3A7 mediated metabolism of a marker substrate.”
An in vitro evaluation of human cytochrome P450 3A4 and P-glycoprotein inhibition by garlic.“ Garlic oil supplement at 5 or 50mg garlic oil/kg bodyweight significantly prolonged bleeding time and thrombin time, and enhanced anticoagulation factor activity, such as antithrombin III and protein C (P<0.05).”
Effect of diallyl trisulfide-rich garlic oil on blood coagulation and plasma activity of anticoagulation factors in rats.
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