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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Ganciclovir
supplement:
Apigenin
Research Papers that Mention the Interaction
“Tumor-bearing mice given only two or three injections of lovastatin or apigenin during GCV treatment had a doubling of the antitumor response rate, with 60-70% of the mice achieving complete remission.”
Enhancement of the herpes simplex virus thymidine kinase/ganciclovir bystander effect and its antitumor efficacy in vivo by pharmacologic manipulation of gap junctions.“Treatment … apigenin also significantly inhibited the [Ca(2+)](i) response induced by 50 mM KCl solution, decreased … [Ca(2+)](i) responses induced by the metabotropic glutamate receptor agonist, (S)-3,5-dihydroxyphenylglycine ( DHPG , 100 microM, 90 s), and inhibited the caffeine (… mM, 2 min)-induced [Ca(2+)](i) responses.”
Effects of Apigenin on Glutamate-induced [Ca](i) Increases in Cultured Rat Hippocampal Neurons.
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