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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Gamma-Tocopherol and Vitamin E

supplement:

Gamma-Tocopherol

supplement:

Vitamin E

Research Papers that Mention the Interaction

Supplementation with alpha-tocopherol increased serum alpha-tocopherol levels, while producing a marked decrease in serum gamma-tocopherol.
Clinical science  •  2002  |  View Paper
These data support the hypothesis that alpha-tocopherol modulates xenobiotic metabolism by increasing Cyp3a expression, gamma-CEHC formation, and the excretion of both gamma-tocopherol and gamma-CEHC.
Free radical biology & medicine  •  2005  |  View Paper
Recent evidence indicates that gamma-tocopherol may be a more powerful chemopreventive than the alpha-tocopherol.
Current drug targets  •  2003  |  View Paper
Furthermore, we assume that alpha-Toc may affect the metabolism of gamma-Toc to gamma-CEHC in the body.
Lipids  •  2001  |  View Paper
Secondly, the use of alpha-tocopherol supplements significantly reduces serum gamma-tocopherol , and this may have important biological effects.
Critical reviews in food science and nutrition  •  2010  |  View Paper
AT supplementation significantly decreased GT levels.
Plasma AT and GT levels increased following supplementation with AT alone or GT alone or in combination.
Free radical biology & medicine  •  2008  |  View Paper
BACKGROUND Gamma-tocopherol has unique properties that may be beneficial in sustaining optimal human health, but hepatic vitamin E metabolism enhances gamma-tocopherol turnover.
The American journal of clinical nutrition  •  2008  |  View Paper
RESULTS Neutrophil alphaT and ga maT in creased (both P <0.001) with mix ed tocopherol su pplementation, whereas alphaT (P <0.001) increased and gammaT decreased (P <0.005) after alphaT supplementation.
Clinical chemistry  •  2007  |  View Paper
Supplementation with alpha-tocopherol caused alpha-tocopherol levels to rise (13.2 +/- 3.7 to 27.3 +/- 14 mug/mL), but gamma-tocopherol levels to decrease (4.1 +/- 1.6 to 3.5 +/- 1.1 mug/mL).
American journal of kidney diseases : the official journal of the National Kidney Foundation  •  2007  |  View Paper
Vitamin E in supplements is mostly alpha-tocopherol , which may block the antioxidant activity of gamma-tocopherol and have a pro-oxidant effect in vivo.
Obstetrics and gynecology  •  2006  |  View Paper
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