supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
supplement:
Gamma-Tocopherol
drug:
Nitric Oxide
Research Papers that Mention the Interaction
“ NO and ascorbate spared both alpha-TOH and gamma-TOH through independent and additive mechanisms.”
Peroxynitrite-mediated alpha-tocopherol oxidation in low-density lipoprotein: a mechanistic approach.“In conclusion, our data show that NO inhibits growth and insulin secretion in RINm5F cells, and that gamma-tocopherol may partially prevent this.”
“Pretreatment with gamma-tocopherol (but not alpha-tocopherol) afforded a partial protection against the inhibitory effects of NO , whereas specifically inhibiting inducible NO synthase with N-nitro-L-arginine completely reversed the IL-1beta effects.”
gamma-tocopherol partially protects insulin-secreting cells against functional inhibition by nitric oxide.“We propose that gamma-tocopherol exerts its influence on seedling development by controlling the content of nitric oxide ( NO ) in germinating seeds.”
The impact of tocochromanols on early seedling development and NO release.“Both a- and gamma-tocopherol increased NO generation and cNOS activity (all P <.05 vs control).”
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback