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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
supplement:
Gamma-Aminobutyric Acid
drug:
Triazolam
Research Papers that Mention the Interaction
“We found in this study that even the beta 2 gamma 2 subtype displays gamma-aminobutyric acid-induced Cl- currents that are potentiated by triazolam (a triazolobenzodiazepine).”
Potentiation of gamma-aminobutyric acid-induced chloride currents by various benzodiazepine site agonists with the alpha 1 gamma 2, beta 2 gamma 2 and alpha 1 beta 2 gamma 2 subtypes of cloned gamma-aminobutyric acid type A receptors.“The chronic administration of three daily doses of Triazolam produced a decrease in GABA levels in all brain regions studied.”
Effects of acute and chronic triazolam treatments on brain GABA levels in albino rats.“ Triazolam produces its effects through potentiation of γ‐aminobutyric acid‐mediated neurotransmission.”
“ Triazolam and the quinolizinone Ro 19-8022 potentiated the effect of GABA maximally by nearly 50%, diazepam by about 40% and bretazenil by approximately 20%.”
“In the present study, the possibility that the differences in the effects of pentobarbital on the circadian rhythm may be due to different contributions … by compar ing the responses of SK mice with those of C57BL mice to muscimol (2 mg/kg), a GABA receptor agonist, and triazolam (… GABA.”
“At 1-10 microM, triazolam also reduced the charge transfer triggered by GABA in outside-out patches of spinal cord cell membrane.”
“We also investigated (1) the effect of fluoxetine on visual and motor cortex excitability and (2) the impact of increased GABA mediated inhibition following a single dose of triazolam on post-training MDD task performance.”
Fluoxetine Does Not Enhance Visual Perceptual Learning and Triazolam Specifically Impairs Learning Transfer
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