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Discover Supplement-Drug Interactions
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Last Updated: 5 years ago
supplement:
Gamma-Aminobutyric Acid
drug:
Tranquilizing Agents
Research Papers that Mention the Interaction
“In vivo, various anxiolytic drugs exhibit a wide range of variability in their modulatory efficacy and potency of GABA action.”
Molecular mechanisms of the partial allosteric modulatory effects of bretazenil at gamma-aminobutyric acid type A receptor.“There is increasing evidence that anxiolytic drugs produce their pharmacological effects by enhancing brain gamma-aminobutyric acid (GABA) transmission.”
“In this paper the evidence is considered for a possible involvement of GABA in the behavioral effects of anxiolytic drugs.”
GABA and the behavioral effects of anxiolytic drugs.“The total increase in the GABA level in the nerve terminals is suggested to be important for the development of the anxiolytic effect of tranquilizers.”
“The ability of clonazepam, like other tranquilizers of the benzodiazepine series, to augment the sensitivity of the receptive neurons formations to gamma-aminobutyric acid and also influence the ionic permeability of the post-synaptic membrane is suggested.”
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