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Discover Supplement-Drug Interactions

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Last Updated: 3 months ago

Possible Interaction: Gamma-Aminobutyric Acid and Tranquilizing Agents

Research Papers that Mention the Interaction

In vivo, various anxiolytic drugs exhibit a wide range of variability in their modulatory efficacy and potency of GABA action.
Proceedings of the National Academy of Sciences of the United States of America  •  1992  |  View Paper
There is increasing evidence that anxiolytic drugs produce their pharmacological effects by enhancing brain gamma-aminobutyric acid (GABA) transmission.
The Lancet  •  1982  |  View Paper
In this paper the evidence is considered for a possible involvement of GABA in the behavioral effects of anxiolytic drugs.
Life sciences  •  1985  |  View Paper
The total increase in the GABA level in the nerve terminals is suggested to be important for the development of the anxiolytic effect of tranquilizers.
Biulleten' eksperimental'noi biologii i meditsiny  •  1981  |  View Paper
The ability of clonazepam, like other tranquilizers of the benzodiazepine series, to augment the sensitivity of the receptive neurons formations to gamma-aminobutyric acid and also influence the ionic permeability of the post-synaptic membrane is suggested.
Farmakologiia i toksikologiia  •  1978  |  View Paper