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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Gamma-Aminobutyric Acid
drug:
Tramadol
Research Papers that Mention the Interaction
“As described in both articles presented by Dr. M egarbane, there is evidence of GABA inhibition by tramadol.”
In reply to Dr. Chhabra, Dr. Mégarbane, and colleagues“Coadministration of either gamma-aminobutyric acid (GABA)-ergic drugs (diazepam, GABA, muscimol and baclofen) or N-methyl-D-aspartate (NMDA) receptor antagonist, MK801 with tramadol augmented the anticonvulsant effect of the latter drug.”
On the mechanism of anticonvulsant effect of tramadol in mice
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