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Discover Supplement-Drug Interactions
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Last Updated: 5 years ago
supplement:
Gamma-Aminobutyric Acid
drug:
Thyroxine
Research Papers that Mention the Interaction
“Compared with the negative control group, GABA treatment groups showed significantly upregulated T4 , T3 and TBG levels (42.34 μg/l, 6.54 ng/ml and 18.78 ng/ml, respectively; P<0.05), properly increased TSH level and apoptosis inhibition in thyroid follicular epithelial cells.”
γ-Aminobutyric acid ameliorates fluoride-induced hypothyroidism in male Kunming mice.“Studies of the effects of thyroid hormones on the uptake of neurotransmitters by homogenates of rat cerebral cortex have revealed a significant competitive inhibition of neuronal uptake of [3H]GABA by thyroid hormones (T3 greater than T4 greater than rT3).”
“In purified synaptosomes, T3, T4 , and rT3 blocked GABA uptake when added simultaneously with GABA and also after preincubation and washing before addition of GABA, thus indicating that binding of hormones had occurred.”
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