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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
supplement:
Gamma-Aminobutyric Acid
drug:
Theophylline
Research Papers that Mention the Interaction
“Although the exact mechanism for seizure induction cannot be determined from these cases, potential drug interactions exist, because theophylline , imipenem, and ciprofloxacin are all believed to increase excitation of the central nervous system by inhibition of γ-aminobutyric acid binding to receptors.”
Seizures in Patients Simultaneously Receiving Theophylline and Imipenem or Ciprofloxacin or Metronidazole“We report the finding that chronic exposure of embryonic brain neurons to caffeine or theophylline reduces the ability of gamma-aminobutyric acid ( GABA ) to potentiate the binding of [3H]flunitrazepam to the GABA/benzodiazepine receptor.”
Chronic caffeine or theophylline exposure reduces gamma-aminobutyric acid/benzodiazepine receptor site interactions.
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