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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Gamma-Aminobutyric Acid
supplement:
St John's Wort
Research Papers that Mention the Interaction
“ St. John's wort extract has a clear inhibitory effect on the neuronal uptake not only of serotonin, noradrenaline, and dopamine but also of gamma-aminobutyric acid (GABA) and L-glutamate.”
Current St John's wort research from mode of action to clinical efficacy.“In our previous investigations, we could demonstrate that extract preparations of Hypericum perforatum (St. John's wort, SJW) inhibit the uptake of several neurotransmitters (serotonin, norepinephrine, dopamine, GABA , L-glutamate) in synaptosomal preparations of rodent brain.”
Evaluation of synaptosomal uptake inhibition of most relevant constituents of St. John's wort.
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