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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Gamma-Aminobutyric Acid
drug:
Sirolimus
Research Papers that Mention the Interaction
“ GABA inhibits the selective autophagy pathways, mitophagy and pexophagy, through Sch9, the homolog of the mammalian kinase, S6K1, leading to oxidative stress, all of which can be mitigated by the Tor1 inhibitor, rapamycin.”
Defects in GABA metabolism affect selective autophagy pathways and are alleviated by mTOR inhibition
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