Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Current topics in behavioral neurosciences • 2012 | View Paper
“Schild plot analyses of the inhibitory actions of dopamine and serotonin on currents elicited by GABA showed slopes of 2.7 ± 0.3 and 6.1 ± 1.8, respectively, indicating a noncompetitive mechanism of inhibition.”
“More recently it has been shown that some neurons contain more than one classical transmitter, e.g. 5-HT plus GABA , further underlining the view that transfer of information across synapses may be more compex than perhaps hitherto assumed.”
“Furthermore, endogenous noradrenaline and GABA tonically regulate the extracellular concentration of 5-HT although the degree of tonicity appears to depend upon the sleep/wake cycle and the behavioral state of the animal.”
“… GABA has an inhibitory effect … as norepinephrine and serotonin and this inhibition may be involved in local circuits and interneurons, it has been suggested that the hypothesis of a … does not compete with but complements the well-established hypotheses of alterations in noradrenergic and serotonergic function in mood disorders.”
“Thus, we propose that 5-HT2C receptors inhibit GABAA receptors by a Ca(2+)-dependent, but phosphorylation independent, mechanism and that 5-HT and GABA may act as cotransmitters to regulate neuronal activity.”
Progress in clinical and biological research • 1985 | View Paper
“There is evidence that neurotransmitters function in mouse palate development: Serotonin and acetylcholine stimulate and GABA inhibits shelf reorientation.”
American journal of mental deficiency • 1984 | View Paper
“An action on the GABA synapse may account for alterations in the effects of other neurotransmitters, such as norepinephrine, serotonin , and acetylcholine.”