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Last Updated: 2 years ago

Possible Interaction: Gamma-Aminobutyric Acid and Scopolamine

Research Papers that Mention the Interaction

However, when carbachol was injected in the presence of picrotoxin or GABA was injected in the presence of scopolamine , the effect of GABA or picrotoxin was dominant.
Neuroscience  •  2001  |  View Paper
Simultaneous administration of GABA agonists with sub-effective doses of anticholinergic agent (scopolamine) did not potentiate antitremor effect of scopolamine, whereas GABA antagonists and effective doses of scopolamine when administered simultaneously resulted in antagonism of protective effect of scopolamine.
Methods and findings in experimental and clinical pharmacology  •  1988  |  View Paper
Scopolamine and tetrodotoxin completely inhibited the acid secretion induced by low concentrations of GABA and muscimol and to some extent the response induced by high concentrations of muscimol.
The American journal of physiology  •  1987  |  View Paper
At a concentration of 0.1 mmol/L, atropine and scopolamine had only small inhibitory effect reducing the uptake of [3H]GABA to 62%, but syntropan (IC50 5 micromol/L) was more potent inhibitor than flurazepam (IC50 120 micromol/L) in vitro.
Zhongguo yao li xue bao = Acta pharmacologica Sinica  •  1986  |  View Paper
4 The bicuculline‐insensitive relaxation induced by GABA and (—)‐baclofen was prevented by tetrodotoxin and hyoscine but not by phentolamine plus propranolol, naloxone or theophylline.
British journal of pharmacology  •  1983  |  View Paper
Contractions in response to GABA were blocked by hyoscine.
European journal of pharmacology  •  1980  |  View Paper
GABA (1×10 −3 M) facilitated the K + 17mM evoked release of ACh and potently enhanced the stimulating action of hyoscine.
Pharmacological research communications  •  1980  |  View Paper