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Discover Supplement-Drug Interactions

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Last Updated: 4 months ago

Possible Interaction: Gamma-Aminobutyric Acid and Pyrithioxin

Research Papers that Mention the Interaction

Pyritinol did not influence GABA transaminase activity, but lessened the oxidation of GABA to carbon dioxide.
Physiologia Bohemoslovaca  •  1988  |  View Paper
Depression of the affinities of GABA and the associated benzodiazepine receptor, together with inhibition of GABA synthesis, in the presence of pyritinol indicate that diminished activity of the GABA system in the brain might be related to the activating effect of pyritinol.
In 100 and 200 mumol/l concentration, pyritinol inhibited GABA binding to the GABA receptors of brain synaptosomal membranes.
Physiologia Bohemoslovaca  •  1988  |  View Paper