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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Gamma-Aminobutyric Acid
drug:
Pimozide
Research Papers that Mention the Interaction
“After short-term pimozide treatment, GABA levels in all patients were raised, albeit nonsignificantly.”
CSF levels of gamma-aminobutyric acid in schizophrenia. Low values in recently ill patients.“In these subjects, pimozide (6 mg/day, orally, for 4 days) significantly blunted the GH elevation induced by GABA (P < 0.01).”
“Injection of GABA , but not baclofen (a GABAB agonist), stimulated GTH-II secretion in pimozide or GnRH analogue-pimozide pretreated fish at both 0.5 and 2 h in early prespawning phase except at 0.5 h in the pimozide--GABA (10 micrograms) group.”
Distribution of gamma-aminobutyric acid in catfish (Heteropneustes fossilis) forebrain in relation to season, ovariectomy and E2 replacement, and effects of GABA administration on plasma gonadotropin-II level.“The dopamine antagonist pimozide , but not adrenergic (both alpha and beta), serotoninergic or cholinergic antagonists, prevented the actions of histamine and GABA.”
“A speculative explanation is given for the ability of pimozide to reverse the action of GABA on plasma prolactin.”
“Subthreshold doses of haloperidol, sultopride, metoclopramide and pimozide failed to consistently antagonise peri-oral movements when similarly combined with GABA , serotonin or quipazine.”
“Antagonism of the responses to acetylcholine, dopamine, serotonin and GABA was seen using atropine, pimozide , methysergide and bicuculline respectively.”
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