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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Gamma-Aminobutyric Acid and Phenylalanine

Research Papers that Mention the Interaction

Serial mutations at beta(2)97 revealed a approximately 20-fold increase in EC50 with the addition of each fluorine atom to a phenylalanine , indicating a cation-pi interaction between GABA and this residue.
The Journal of neuroscience : the official journal of the Society for Neuroscience  •  2007  |  View Paper
phenylalanine … gammaaminobutyric acid syntheses and that a deficiency of one or more of these potential transmitter substances produces neurological symp toms.'-3 Other workers have suggested that … phenylketonuria, once established, is irreversible, a clinical finding that points to the presence of permanent structural alterations within the central nervous system.
Neurology  •  1968  |  View Paper
Application of glutamate or gamma-aminobutyric acid evoked an alkaline shift in the pHe baseline at P3-P14 as well as after X-irradiation.
Journal of Chemical Neuroanatomy  •  1993  |  View Paper
Application of GABA evoked an alkaline shift in the pHe baseline which was blocked by picrotoxin and in HEPES-buffered solution.
Brain Research  •  1992  |  View Paper
GABA was shown to significantly increase the incorporation of l -[1-14C]leucine, alanine, and phenylalanine into protein by slices and homogenates of cortex and forebrain.
Brain research  •  1973  |  View Paper