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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Gamma-Aminobutyric Acid and Pergolide

supplement:

Gamma-Aminobutyric Acid

drug:

Pergolide

Research Papers that Mention the Interaction

“It was thus concluded that pergolide inhibits calcium-stimulated release of GABA presynaptically by a mechanism distinct from that of tetrodotoxin.”
Pergolide presynaptically inhibits calcium-stimulated release of gamma-aminobutyric acid.
Journal of neurochemistry  •  1991  |  View Paper
“However, while apomorphine and SKF 38393 increased, pergolide decreased the levels of GABA in the striatum.”
The effects of intranigral GABA and dynorphin A injections on striatal dopamine and GABA release: Evidence that dopamine provides inhibitory regulation of striatal GABA neurons via D2 receptors
Brain Research  •  1990  |  View Paper
“Addition of pergolide (10(-4) M) to the perfusion medium decreased the GABA overflow induced by high K+ but apomorphine (10(-4) M) had no effect on the GABA overflow.”
The effect of apomorphine and pergolide on the potassium-evoked overflow of GABA in rat striatum studied by microdialysis.
European journal of pharmacology  •  1986  |  View Paper