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Discover Supplement-Drug Interactions
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Last Updated: 3 months ago
supplement:
Gamma-Aminobutyric Acid
drug:
Niflumic Acid
Research Papers that Mention the Interaction
“The inward currents activated by 100 µmol/l GABA were suppressed by treatment with 1, 10 and 100 µmol/l NFA (5.32±3.51, 33.8±5.20, and 52.2±6.32%, respectively; P<0.05).”
Effects of niflumic acid on γ-aminobutyric acid-induced currents in isolated dorsal root ganglion neurons of neuropathic pain rats“The …/l GABA were attenuated by (0±0.09%; neurons = 4), (5.32±3.51%; neurons = 6), (21.3±4.00%; neurons = 5), (33.8±5.…±5.10%; neurons = 4) and (61.1±4.12%; neurons = 12) by 0.1, 1, 3, 10, 30 and 100 µmol/l NFA, ….”
“In contrast, 10 microM niflumic acid potentiated 10 microM GABA responses by only 30% (EC50 approximately 10 microM) and inhibited maximal responses by 60% (IC50 approximately 7 microM).”
Effects of fenamates and other nonsteroidal anti-inflammatory drugs on rat brain GABAA receptors expressed in Xenopus oocytes.
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