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Discover Supplement-Drug Interactions

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Last Updated: 3 months ago

Possible Interaction: Gamma-Aminobutyric Acid and Niflumic Acid

Research Papers that Mention the Interaction

The inward currents activated by 100 µmol/l GABA were suppressed by treatment with 1, 10 and 100 µmol/l NFA (5.32±3.51, 33.8±5.20, and 52.2±6.32%, respectively; P<0.05).
Experimental and therapeutic medicine  •  2017  |  View Paper
The …/l GABA were attenuated by (0±0.09%; neurons = 4), (5.32±3.51%; neurons = 6), (21.3±4.00%; neurons = 5), (33.8±5.…±5.10%; neurons = 4) and (61.1±4.12%; neurons = 12) by 0.1, 1, 3, 10, 30 and 100 µmol/l NFA, ….
Experimental and therapeutic medicine  •  2016  |  View Paper
In contrast, 10 microM niflumic acid potentiated 10 microM GABA responses by only 30% (EC50 approximately 10 microM) and inhibited maximal responses by 60% (IC50 approximately 7 microM).
The Journal of pharmacology and experimental therapeutics  •  1994  |  View Paper