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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Gamma-Aminobutyric Acid and Nefiracetam

Research Papers that Mention the Interaction

Systemic administration of NEF significantly attenuated the elevated PICs, amplified GAT-1 and GAT-3 as well as impaired GABA.
Cellular Physiology and Biochemistry  •  2015  |  View Paper
Therefore, nefiracetam and galantamine are hypothesized to cause stimulations of the glutamate and GABA systems via stimulation of nAChRs.
Neuroscience  •  2009  |  View Paper
Repeated administration of nefiracetam increased ChAT activity, gamma-aminobutyric acid (GABA) turnover and glutamic acid decarboxylase activity, and facilitated the Na(+)-dependent high-affinity GABA uptake.
Behavioural Brain Research  •  1997  |  View Paper
The desensitization of the GABAA receptor at high concentration (100 microM) of GABA was accelerated by nefiracetam.
Neuropharmacology  •  1996  |  View Paper