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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Gamma-Aminobutyric Acid
supplement:
NAD
Research Papers that Mention the Interaction
“ NAD stimulated GABA formation in dialyzed extracts, and inhibition of GABA-transaminase, bothin vitro andin vivo, caused marked inhibition of GABA formation from glutamate in peripheral extracts.”
Glutamate as a precursor of GABA in rat brain and peripheral tissues“10(-3) M and 10(-6) M NAD concentrations decrease GABA uptake by 30% and 24%.”
“ GABA causes reduction of intra‐mitochondrial NAD+ ; glutamate or 2‐oxoglutarate stimulate this reduction at concentrations at which they do not themselves cause reduction.”
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